A study of sleep disturbances in patients with multidrug-resistant tuberculosis

Abstract

Background: Sleep is one of basic biological needs, and mental and physical illness, stress, medication, genetic factors, age, night shift work, and bad habits cause sleep disturbance. Multi-drug resistant patients face depression, anxiety and sleep disturbance. Even though mental health, depression and anxiety of MDR-TB patients were studied in our country, sleep disturbance were not studied yet. Goal: To study sleep disturbance among multi-drug resistant tuberculosis patients Materials and method: This study used a randomly assigned case control study. A total of 83 MDR-TB patients who enrolled treatment between 2020 and 2021 in Mongolia participated in this study. We used Sleep disturbance standard test, Zung Self-Rating depression Scale, Zung Self-rating anxiety scale, AUDIT, Fagerstorm test and assessed scale reliability by calculating Cronbach1s alpha. Results: A total of 83 MDR-TB patients were participated in our study and 57% were males, 23% were between 35 and 44 age group, the mean age of patients an age was 40.11 ± 1.5, 62% have secondary education, 57% were married, 40% were unemployed. Sleep disturbance standard test result shows that 45% of all participants have sleep disturbance (Cronbach`s alpha=0.574). Bivariate analysis shows that alcohol dependence was significantly associated with sleep disturbance. Conclusion: In this study, MDR-TB patients have sleep disturbance during MDR-TB treatment and patient, who has alcohol use disorder, face sleep disturbance.