Results of a study of the relationship between body mass index and clinical parameters of inpatients with Covid-19

Abstract

Background: Obesity is an increasing worldwide health concern and is regarded as a critical risk factor for various infections, post infection complications and mortality from severe infections. Obesity has also been shown to affect lung function in multiple ways that are related to mechanical and inflammatory factors, making obese individuals more likely to suffer from respiratory symptoms and progress to respiratory failure. Aim: to study the association between BMI and some vital and laboratory finding COVID-19 Materials and Methods: The study was conducted among 1.600 people admitted to the Covid-19 isolation inpatients of the Central Hospital of the Mongolian National University of Medical Sciences. The survey data were collected from April 2021 to August 2021. Results: The mean age of the respondents was 42.1±14.7 and 54.5% were male. In terms of severity, 24.7% were mild, 54.5% were moderate, and 20.8% were severe. The mean BMI of the respondents was 25.5±4.9 and 51.7% were normal weight wils, 31.6% and 16.5% were overweight and obese respectively. Considering the relationship between BMI and Covid-19 severity, 28.6% of obese people and 14.3% of normal weight people were diagnosed and treated with severe disease (p=0.032). We have observed that a strong relationship between BMI and COVID-19 severity: BMI 24.1±5.0 mild, 25.4±4.8 moderate and 27.7±5.1 severe. Regarding to BMI category, some vital sings (SpO2, RR, SBP) and laboratory result (WBC, PLT, Lymph, serum ferritin) were significantly severe in obese people compere to normal weight (P<0.01) Conclusion: Overweight and obesity are independently increasing the adverse impact of COVID-19. In Patients with obesity indicating an urgent and continued need to mitigate severe acute respiratory syndrome COVID-19 infection risk in this community.