Incidence of lymphoma and B cell non-Hodgkin’s lymphoma among adults in Mongolia between 2015-2019

Abstract

Background: It has been well known that the development of B-Cell Non-Hodgkin Lymphoma (B-NHL), the most common malignancy in lymphoma, is influenced by patient’s age, gender, and viral hepatitis status. Materials and Methods: We have retrospectively studied 363 lymphoma patients who met study criteria and were diagnosed between 2015 and 2019. And we compared B-NHL patients with Hodgkin lymphoma (HL) and T-Cell Non-Hodgkin Lymphoma (T-NHL) patients, for their age, gender, and viral hepatitis status. Results: Out of all 363 lymphoma patients, 284 (78.2%), 45 (12.4%), 34 (9.4%) patients were diagnosed with B-NHL, HL, and T-NHL, respectively. And 185 were male and average age was 53.3. But average age in HL patients were much younger than B-NHL patients (44.4 vs 55.1; p<0.000). Then, HBsAg positivity was similar in 3 groups (14.4% vs 11.1% vs 5.9%; p=0.344), while, anti-HCV was determined with higher percentage in B-NHL patients compared to other 2 groups (42.6% vs 17.8% and 17.7%; p<0.000). In B-NHL patients, the prevalence of anti-HCV was significantly higher than in the general population (42.6% vs 11.1%; p=0.000). In addition, there were no significant difference between age, gender, and viral hepatitis status among B-NHL patients, and their incidence of each year (p>0.05). Conclusion: The incidence of B-NHL 2.87 per 100,000 Mongolian adult population is lower than the world average (4.82). However, the prevalence of hepatitis virus infection is high among them.