Evaluation of COVID 19 vaccination effectiveness among pregnant woman

Abstract

Background: Major International Organizations such as the World Health Organization (WHO), Centers for Disease and Prevention (CDC), Americal College of Obstetrics and Gynecology (ACOG) recommend that use of Covid 19 vaccine for people who are pregnant, breastfeeding and trying to get pregnant. Aim: To determine the effectiveness of COVID 19 vaccine among pregnant woman. Materials and Methods: In this prospective study, we collected data from pregnant woman between July 1, 2021 and January 20, 2022. The survey data were collected four categories of questionnaires followed by two interviews. Results: Among the total of 420 pregnant woman, 193 (46.0%) have received COVID 19 vaccine and 227 (54.0%) were not. (1:1) Whether to relate between COVID 19 vaccination and COVID 19 infections were statistically significant in differentiating to the study groups. Our analysis shows that risk of COVID 19 infections rised by 1.9 (OR=1.91, 95.0% CI: 1 – 3.6, p=0.05) times in unvaccinated group compared with pregnant woman who received COVID 19 vaccine. According to the result, COVID 19 vaccine has an effectiveness of 91% for the pregnant woman if they continue to administer the prevention method of COVID 19 infections (same as before the vaccination: wearing a mask, keep a safe distance). Conclusions: In this study, COVID 19 vaccines have became a crucial tools for reducing the incidence of COVID 19 infection in pregnancy