Determination of C reactive protein in the blood of pregnant women

Abstract

Background: Prenatal exposure to air pollution can have many adverse effects and increase risks of cardiovascular and respiratory diseases. Therefore, it is necessary to determine the CRP protein in the blood of pregnant women living in areas with high air pollution. Materials and Methods: The survey covered 404 pregnant women of the Sukhbaatar district of Ulaanbaatar. We installed air purifiers in some of the participants› homes. Indoor PM2.5 was measured twice at 10 and 30 weeks of gestation. We collected dried blood spots from participants and tested the CRP, and conducted questionnaires. Statistical analysis was performed with STATA 15. Results: The mean age of participants in the study was 29 ± 5.4, of whom 80.4% had higher education, 60.5% were married, and 72.3% had BMI 18.5 to 25. CRP in the dried blood spots of women in the intervention group was 0.44 mg/L (p> 0.05) lower than in the control group. CRP of participants living with a smoker at home was 0.13 mg/l higher (p> 0.05). When PM2.5 concentration increases by 1 μg/m3, the blood-CRP protein increases by 0.02 units. Participants who were overweight had the highest concentration of CRP was 4.68 mg/l. Conclusion: CRP in pregnant women is reduced by reducing indoor air pollution. Increased body mass index in pregnant women leads to an increase in reactive protein C in the blood.