B-value diffusion weighted MRI for staging alcoholic liver cirrhosis

Abstract

Background: Until today perfect methods for the early diagnosis of alcohol-induced cirrhosis has not been developed. Proper diagnosis of the disease at an early stage, identification of the stage and timely treatment are very important to slow down the progression of cirrhosis and cancer. Objectives: To determine the stage of cirrhosis using a variety of b-values in a weighted sequence of alcohol-induced cirrhosis with 3.0T CPT. Materials and Methods: 60 patients with clinically and clinically confirmed alcohol-induced cirrhosis were randomly selected. In the two comparative control groups, 5 types of b-values (200 s/mm², 400 s/mm², 600 s/mm², 800 s/mm², 1000 s/mm²) and measured hepatic ADC at different b-values. Results: In alcohol-induced cirrhosis, the ADC of the hepatic parenchyma is lower in all groups of the Child Pew class than in the control group under different b-values. At the same b value, the ADC value gradually decreases or is inversely related to the severity of alcohol-induced cirrhosis. The difference in ADC between the control group and the alcohol-induced hepatic cirrhosis group was statistically significant (p <0.05) under the different b values. Conclusion: Decreases in ADC during the DWI regimen of CPT are inversely related to the severity of alcohol-induced cirrhosis. At b = 600s / mm², the accuracy of the DWI diagnosis of cirrhosis in patients with alcohol-induced cirrhosis is higher than that of other b-value conditions, resulting in a relatively good DWI image. Therefore, a value of b of 600 s / mm² was determined to be the optimal b value for liver DWI imaging.