Evaluation of protein activity in placental specimens during normal and postterm pregnancies

Authors

  • Э.Саруулсайхан Анагаахын Шинжлэх Ухааны Үндэсний Их Сургууль Author
  • Д.Амгаланбаатар Анагаахын Шинжлэх Ухааны Үндэсний Их Сургууль Author
  • Т.Балжинням АУХ. Эрдэм Шинжилгээний төв лаборатори Author
  • Ж.Энхцэцэг Анагаахын Шинжлэх Ухааны Үндэсний Их Сургууль Author
  • С.Энэбиш Анагаахын Шинжлэх Ухааны Үндэсний Их Сургууль Author

Keywords:

SHP-2, P-38, protein activation

Abstract

Background: Although the role of SHP-2 protein in placental growth is unknown the role of SHP-2 protein remains unclear. Objective: Determination of SHP2 and p-p38 protein activity in placental samples. Methods: The concentration of protein isolated from placental tissue was determined using an ELISA reader in a BCA test album. The activity of SHP2 and p-p38 proteins in placental samples was determined by immunoblotting. Results: Immunoblotting results showed that the production of SHP2 protein varied in the placental specimens of the normal and postterm pregnant group. No activity of phosphorylated p38 protein, an inflammatory transcription factor, was detected in placental specimens during normal andpostterm pregnant group. Conclusion: SHP2 protein synthesis isuniform in placental specimens postterm pregnant. P38 protein not found to be active in the placenta items postterm pregnant.

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Author research profiles: Д.Амгаланбаатар, С.Энэбиш

Боть 17, №7 (63) 2021

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Published

2021-06-10

Issue

Vol. 17 No. 7 (2021)

Section

Original Articles

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Articles in this journal are published under the Creative Commons Attribution 4.0 International License (CC BY 4.0). Anyone may copy, distribute and adapt the work, provided the authors and the source are properly credited. Copyright remains with the authors.