Lipid Profiles in Different ABO Blood Groups in Blood Donors

Abstract

Background and aim: The ABO blood group is the most important system with various distributions reported for different populations. The ABO is known also to be associated with various diseases. In this study, we evaluated the relationship between the ABO blood group and lipid profile. Materials and methods: This was a cross-sectional study. A total number of 120 healthy blood donors underwent laboratory testing by SD Lipidocare analyser which included assessment of total cholesterol, high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c). Results and discussion: The most relevant finding was the identification of significantly higher values of total cholesterol and LDL-c in subjects with blood group A compared with those with other blood type. Analysing the data by blood group showed that the levels of HDL-c were significantly higher in male and female individuals in blood group AB than other groups (P<0.05). Conclusion: This study shows that blood group AB individuals have significant elevated serum HDL-c level compared to the remaining blood groups but AB individuals have significant elevated serum LDL-c level and total cholesterol level.