Result of survival rate of patients with laryngeal cancer

Abstract

Background: In Mongolia, laryngeal cancer (LC) is the 10th most common cancer, with 80% diagnosed late. The main causes of laryngeal cancer are chronic alcohol and tobacco use, toxic working conditions, air pollution, human papillomavirus infection, and gastroesophageal reflux disease. The current study was conducted to evaluate short-term disease control, survival, and functional and oncology outcomes after surgical and nonsurgical combined treatment for patients with laryngeal cancer. Methods: Disease stage and treatment characteristics were analyzed for 64 patients who were sequentially treated for laryngeal squamous cell carcinoma at the single institution between 2014 and 2016. Survival analysis and disease control results wer calculated by Kaplan Meier estimate. Results: Comparing the four stages of clinical mortality, the probability of dying in stage I is 85 percent (0.06) compared to those diagnosed in stage III and 79 percent compared to those diagnosed in stage IV, respectively. (P>0.005) Therefore, compared with clinical stage II, the risk of death was 80 percent lower (P<0.005). In terms of cancer location, the vocal cords were compared with the supraglottic and subglottic. People with supra glottic cancer were 70 percent more likely to die (P>0.005), while people with subglottic cancer were twice as likely to die. (P>0.005) However, when comparing the types of treatment, those who received single treatment lived 2.89 times longer than those who received combination therapy. (P<0.005) Conclusion: 1. Laryngeal cancer survival is strongly dependent on the clinical stage of laryngeal cancer, weak on the type of treatment, cancer location, and the age at diagnosis. 2. The average life expectancy was 1465 days, with a 1-year survival rate of 79%, a 3-year survival rate of 53%, and a 5-year survival rate of 31%.