Cases of Vertically Transmitted Co-Infection

Abstract

Background: Congenital syphilis is an infection caused by transplacental transmission of Treponema pallidum from mother to fetus and remains a significant cause of neonatal morbidity and mortality worldwide. Clinically, it is a multisystem disease with manifestations resembling those of TORCH infections and may also occur as a co-infection with these pathogens. Case Presentation: We report a case of a 28-year-old woman with a prior history of syphilis who had been treated and followed up, presenting with preterm delivery at 31–32 weeks of gestation during her third pregnancy. The neonate subsequently died due to complications associated with a concomitant perinatal infection. Conclusion: Early screening during pregnancy, appropriate follow-up, identification of reinfection, and timely treatment remain key strategies for reducing the burden of congenital syphilis.