An overview of the effects of folic acid metabolism on the skeletal system

Abstract

Folic acid is a water-soluble B vitamin. Folic acid (pteroylmonoglutamic) or vitamin B9 is one of the vitamins that is not synthesized in the human body and it is found in nature in all kinds of green leafy vegetables, fruits, honey, milk, dairy products, and plant and animal products such as kidneys and liver. Several studies have shown that the use of folic acid and B12 supplements and that blood levels reduce the risk of fractures are also irrelevant. The aim is to collect and analyze an overview of the studies on the effects of folic acid metabolism on the skeletal system. An overview of the effects of folic acid on bone health published in online sources such as Thomson Reuters, PubMed-central database, google scholar. The use of folic acid supplements in high-risk groups reduces the risk of osteoporosis. However, folic acid deficiency may affect the density and structure of bone minerals, but the mechanism of action has not been established