Anti-Mullerian hormone as a diagnostic marker in infertile women with Polycystic Ovary Syndrome:

Abstract

Objective: To evaluate the role of Anti-Mullerian hormone (AMH) in Mongolian infertility women with Polycystic Ovary Syndrome (PCOS). Methods: Total of 43 females with PCOS were screened among 1350 infertile women All parameters were assessed either with ELISA in 43 infertile PCOS women and 17 age matched apparently healthy controls diagnosed according to Rotterdam consensus. Results: The incidence of PCOS among 1334 infertile women is 8.7%. Mean age of the patients were 27±3.5 yr, duration of infertility 4.0±2.1yr, BMI 26.7±6.5, overweight 27.9% and 27.9% of them were obese. Among patients 51.2% of them have prolonged menstruation, 44.2% with amenorrhea, and 46.2% with hirsutism and acne 18.6%. As a result of hormone assays were LH 8.9IU±3.5, LH/FSH 1.6 ±0.83 [0.1-3.6], AMH 8.1ng/ml ±4.7 /2.9-21.0/. Biochemical tests shown that mean fasting blood glucose 5.1mmol/L±1.7, HDL2.5mmol/L±0.86, LDL 1.2mmol/L±0.49, cholesterol level 4.6mmol/ L±0.63 and TG 1.6mmol/L±0.7. Ultrasound examination has shown that mean antral follicle count were 21.1±1.8. Conclusion: There should be a future trend of using AMH as a diagnostic marker for PCOS in infertility woman.