Echocardiographic changes in chronic kidney disease patients

Abstract

The aim of this study was to identify the major echocardiographic abnormalities in end-stage renal disease patients, who are undergoing hemodialysis treatment. A cross-sectional study was conducted in cardiology department of Second General hospital that including 60 patients from renal department. In that, 35 patients were undergoing hemodialysis treatment and 25 non-hemodialysis patients but with chronic kidney disease. In our study 50% were men, 28.8% were under the age of 60 and elderly patients over 75 was only 6.5%. As predicted, there are significant difference in LV wall thickness and LV hypertrophy in patients who are undergoing hemodialysis treatment (P<0.0001, P=0.024) comparing to the patients that not on maintenance of hemodialysis. However, no specific changes in statistical meaning of LV diastolic dysfunction in these two groups. Due to Multiple risk logistic regression LV hypertrophy is 6.59 fold bigger in the hemodialysis group than the chronic kidney disease population (P=0.01). Therefore, patients on maintenance of hemodialysis have 13.07 fold greater thickened LV wall than the opposing group (P<0.0001). That means physicians might need to consider reducing the heart load in patients undergoing hemodialysis treatment and start effective treatment of heart failure as it needed. In our study, 78% of all the hemodialysis patients are LV wall thickened and LV hypertrophy (42%), Diastolic dysfunction occupied 62%.