Post-operative colorectal cancer 5 year survival rate in national cancer center of mongolia

Abstract

Introduction: Overall colorectal cancer incidence rate was 3.6% in National Cancer Center of Mongolia, colorectal cancer incidence rates have slightly increased in recent years. According in cancer stages, 5 year survival rate of late stage cancer showed 51%, in early stage cancer showed 79%(American Cancer Society, 2017). In Mongolia, the overall cure rate of colorectal cancer has not examined, precisely. 5 year survival rate of colorectal cancer in Asia showed 60% (Bijan et al, 2012). This study therefore investigated the survival rate of colorectal cancer and its prognostic factors among at National Cancer Center of Mongolia. Method: In this retrospective cohort study, total of 108 patients diagnosed with CRC from 2013 to 2015 at the General Surgery Department of NCCM were employed. The survival graphs were obtained using the Kaplan-Meier method and compared by the Log-rank test. Results: The median survival time was 42 months 95% Cl (38.55-45.66). The overall survival for CRC over the 5 years period was 59.3%. The survival rates of at the I, II, III, IV stages were 100%, 75%, 64.4%, respectively 12.5%. There was a significant difference in the survival rate of colorectal cancer according to the all stages (p=0.0001). During an adjuvant chemotherapy the social and clinical factors (p=0.0003) was the significant social and clinical factors influencing the overall survival. Pathological factors such as TNM tumor stage (p=0.0001), distant metastasis (p=0.0001) were significantly associated with overall survival. Conclusion: Survival rate of colorectal cancer in NCCM is identical as in Asia. Significant clinical and pathological prognostic factors were; adjuvant-chemotherapy, aging, TNM tumor stage, lymph node metastasis, distances metastasis. This study showed that we need for promote awareness about surgery of colorectal cancer and comprehensive screening programs which will greatly improve survival through early detection.