Review of phytochemical and pharmacological activity studiesof leonurus sibiricus l

Abstract

Leonurus sibiricus L. is a genus of herbaceous plants in the Lamiaceae family and spreads in regions of Asia and America. This plant has been used as a traditional medicinal herb in many countries for the treatment of diabetes, gynecological disorder, hypertension and as a sedative. Leonuris sibiricus L contains bioactive compounds including diterpenes, triterpenes, flavonoids, phenolic acids, alkaloid and iridoid. The alkaloid leonurine is cardiovascular, kidney and neuroprotection effect, anti-diabetic, anti-cancer, uterine contraction, sedative activity. While the phenolic acids, flavonoids and labdane diterpenoids has various pharmacological effects including anti-inflammatory, anti-oxidant, antiatherogenic, anti-bacterial and immunomodulation activity.