The results of detecting and genotyping for Herpes simplex virus and Human papillomavirus

Abstract

Introduction: Diagnostic methods for STIs currently used in Mongolia fail to detect Viral STIs. Therefore, we used a nucleic acid detection method to identify the Herpes Simplex Virus (HSV) and human papillomavirus (HPV)’s an infection and included the results in this report. Materials and methods: This study population was visited STI ambulatory of the National Center for Communicable Diseases (NCCD). A total of 1196 cervical and urethra swab samples were collected, using GenoFlow-STD Array and GeneFlow-HPV Array, DiagCor, HK test kits based on Flow-throw hybridization method. Results: HSV 1\2 detected in 0.8% (9) of total sample population. While HPV 6\11 genotypes were detected in 3.3% (39) of total sample population. Female samples were tested for HPV’s 33 genotypes and HPV was detected in 30.5% (178) and infections were either single or combination of multiple genotypes. Alarmingly, the most commonly detected genotypes were HPV 16 [14.6% (26)], 31[11.2% (20)], 52 [10.1% (18)], and HPV 81[8.9% (16)] which are the high risk genotypes of HPV. Conclusion: HPV infection is high among the general population because HPV was most often detected in asymptomatic patients compared to symptomatic patients.