Study of diagnosis and specific characteristics of Celiac disease among adults

Abstract

Introduction: Celiac disease is an immune disease in which people can't eat gluten because it will damage their small intestine. The Celiac disease affects each person differently. Symptoms may occur in the digestive system, or in other parts of the body. One person might have diarrhea and abdominal pain, while another person may be irritable or depressed. Irritability is one of the most common symptoms in children. Some people have no symptoms. At the same time the Celiac disease is genetic. Some people develop a type of skin rash known as dermatitis herpetiformis. Red, raised patches, and blistering may affect the elbows, knees, shoulders, buttocks, and face. Blood tests can help to doctor diagnose the disease. Currently, the only treatment is to avoid gluten for life. With strict observance of the diet, the intestines will normally heal and symptoms disappear, but eating gluten again can cause a relapse. Patients need to be aware which foods contain gluten and which do not, but this may be difÏcult, as many products contain hidden gluten. A qualified dietitian can help a person with celiac disease follow a healthy diet.Our study on the Celiac disease that did in Mongolia has the following conclusions. Hereto: 1. 58% of the people surveyed were children and 42% were adults, and 8% were over 60 years old. 47% of them were male and 53% female. The male and female ratio was 1:1 According to the study, Anti‐tTG sensitivity was 100%; specificity was 98.4% (p <0.05), at the same time Anti-Gliadin sensitivity was 100% and specificity was 73.0% (p <0.05). It meets diagnostic criteria and these two markers have diagnostic importance. 4. Anti-Gliadin and Anti‐tTG were significantly higher than serum biomarkers in patients with celiac disease who participated in the study. Results: A total of 63 respondents were interviewed for laboratory analysis, 18 were interviewed for General analysis of the respondent, for statistical analysis of a 63-year-old total, children aged 0-18 (36) 55.4% and 19-39 years old (11) 16.9 %, 40-59 years old (11) 16.9%, 60-79 years old (3) 4.6%. Of the 63 laboratory tests, 27 or 41.5% were gliadin positive, 4 or 6.2% were ASCA positive, 12 or 18.5% were tTG positive, 9 or 13.8% were PCA positive, and 1 or 1.5% were IF positive. was. When examining the relationship between sex status and laboratory performance, ASCA p <0.05 (p = 0.042) and tTG p <0.05 (p = 0.012), sex was associated with both ASCA and tTG indicators. (p = 0.017), IF p <0.01 (p = 0.000), so age was significantly correlated with PCA and IF parameters. Conclusion: Gliadin positive was positive in 41.5% of those tested, and tTG positive in 18.5% of patients; diarrhea was 72.2%, weight loss was 61.1%, and belly filling was 55.6%. In the laboratory, 38.9% of those who had previously consumed gluten-containing foods or had allergic reactions to other foods, while ASCA and tTG were laboratory-related, while PCA and IF were age-related.