Clinical study to evaluate the effects of RuXian-I medicine the patients with hyperplasia of mammary gland

Abstract

Hyperplasia of mammary gland (HMG) is a common breast diseases in the middle-aged women all over the word and a precancerous lesion of mammary gland (MG). The traditional Mongolian medicine RuXian-I provided by the AfÏliated Hospital of Inner Mongolia University for Nationalities is an empirical formula specifically to use for the treatment of HMG in clinical based on the principles of traditional Mongolian medicine. RuXian-I is composed of 30 ingredients, which are Herba Leonuri Japonici, Fructus Amomi Rotundus, Flos Caryophylli, Fructus Gardeniae, Rhizoma Gymnadeniae Conopseae, Semen Myristicae, Cornu Cervi Pantotrichum, Cordyceps and so on. These herbs themselves have a variety of biological activities, including anti-allergic, anti-oxidant and anti-tumor, anti-inflammation activity. The aim of this study was to evaluate the effects of Mongolian medicine RuXian-I treatment patients with hyperplasia of mammary gland. The clinical trial was carried out at Afhliated hospital of National University of Inner Mongolia, with two parallel groups: a RuXian-I and a Xia Ku Cao. The data’s were analyzed at the baseline, during the 3 and 6 weeks of follow-up by repeated measures analysis of variance. During follow up, the assessments scores of symptoms were significantly decreased to pre-treatment level in both group. RuXian-I medicine reduce the pain and decrease the hyperplasia of mammary gland in patients with hyperplasia of mammary gland.