The results of screening program where burdening gastric cancer

Abstract

Background: Mongolia is the leading country by the incidence and mortality rate of gastric. In 2022 national cancer screening program for upper gastrointestinal neoplasia was initiated therefore we conducted the multi-center study for determining the gastric cancer among Mongolian population. Aim: Our goal is to study the results of early and late stage gastric cancer detection and gastric cancer early detection rate based on gastric endoscopy. Materials and Methods:The retrospective multi-center study was performed to screen the precancerous lesion (LGD, Atypia) and cancerous lesion (HGD, adenocarcinoma, signet cell carcinoma etc.) assessed among the people who underwent gastric endoscopy in 28 endoscopy centers in Mongolia during from May of 2022 to May of 2023. (Endoscopic centers of Ulaanbaatar city’s 9 district and 21 provinces). The primary outcomes of this study was to define detection rate (proportion of positive cases among individuals who underwent endoscopic screening) and to determine the characteristics of cancer type including its precursor disease. Results: Totally 67.634 people were screened from May 2022 to May 2023. Among them n=402 (0.5%) patients diagnosed with gastric cancer based on endoscopic examination. The proportion of early stage gastric cancer was n=229 (56.9%) of all screened cancer cases. Conclusions: 1. The initiation of Mongolian national gastric cancer screening program was useful to detect gastric cancer in early stage which further can reduce mortality rate of gastric cancer due to its treatment possibilities. 2. In terms precancerous changes in the stomach, low gradel dysplastic changes are predominant in the tissue analysis. Therefore, national screening program should be continuous.