Evaluation of mandibular bone healing with platelet rich plasma

Abstract

Purpose: This study radiographically evaluated the performance of autologous platelet-rich plasma [PRP] applied in tooth sockets. Methods: Sixty-eight extractions of bilateral impacted mandibular third molars were performed in 30 patients. In one side the autologous platelet-rich plasma was placed and the other side was filled with a blood clot. Radiographic bone density was quantified 3 times by the same examiner at different moments using ImageJ software, and data was statistically analyzed by SPSS 24.0 software. Results: There was significantly faster bone formation in sockets treated with PRP [P<0.001]. Significant healing was observed in the first month [P<0.004], second month [P< 0.001] for the PRP group. Conclusion: Use of the autologous PRP method can skip the resorptive phase, and proceed bone regeneration. Thus, to prove the results histomorphometric analysis is preferred.